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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTGFR All Species: 21.52
Human Site: S234 Identified Species: 52.59
UniProt: P43088 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P43088 NP_000950.1 359 40055 S234 L L R V K F K S Q Q H R Q G R
Chimpanzee Pan troglodytes XP_513513 359 40064 S234 L L R V K F K S Q Q H R Q G R
Rhesus Macaque Macaca mulatta XP_001104323 359 40044 S234 L L R V K F K S Q Q H R Q G R
Dog Lupus familis XP_542174 343 37199 A220 L L N T I S V A T L C H V Y H
Cat Felis silvestris
Mouse Mus musculus P43117 366 40681 S234 L L R V K F R S Q Q H R Q G R
Rat Rattus norvegicus P43118 366 40636 S234 L L R V K F R S Q Q H R Q G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512014 366 41408 G234 L L R V K F K G Q Q H R Q G R
Chicken Gallus gallus NP_001038122 364 40949 S232 L L R V K F K S Q Q R Q G R S
Frog Xenopus laevis NP_001108252 367 41963 L241 H I E M I I Q L L A I M C V S
Zebra Danio Brachydanio rerio XP_700529 390 43934 L231 L L R S R V Q L D R N N H R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.3 31.7 N.A. 87.6 85.5 N.A. 84.6 80.4 68.3 47.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 98.8 49 N.A. 93.7 92.9 N.A. 90.7 88.1 81.1 62.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 93.3 93.3 N.A. 93.3 66.6 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 100 N.A. 93.3 73.3 20 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 0 10 60 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 60 10 10 0 20 % H
% Ile: 0 10 0 0 20 10 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 70 0 50 0 0 0 0 0 0 0 0 % K
% Leu: 90 90 0 0 0 0 0 20 10 10 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 20 0 70 70 0 10 60 0 0 % Q
% Arg: 0 0 80 0 10 0 20 0 0 10 10 60 0 20 60 % R
% Ser: 0 0 0 10 0 10 0 60 0 0 0 0 0 0 20 % S
% Thr: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 70 0 10 10 0 0 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _